Now showing items 1-2 of 2

    • C-src kinase inhibition reduces arrhythmia inducibility and connexin43 dysregulation after myocardial infarction. 

      Rutledge, Cody A.; Ng, Fu Siong; Sulkin, Matthew S.; Greener, Ian D.; Sergeyenko, Artem M.; Liu, Hong; Gemel, Joanna; Beyer, Eric C.; Sovari, Ali A.; Efimov, Igor R.; Dudley, Samuel C. (Elsevier, 2013-11)
      Objectives: the aim of this study was to evaluate the role of c-src inhibition on connexin43 (cx43) regulation in a mouse model of myocardial infarction (mi). Background: mi is associated with decreased expression of ...
    • Mitochondrial Dysfunction Causing Cardiac Sodium Channel Downregulation in Cardiomyopathy 

      Liu, Man; Gu, Lianzhi; Sulkin, Matthew S.; Liu, Hong; Jeong, Euy-Myoung; Greener, Ian; Xie, An; Efimov, Igor R.; Dudley, Samuel C. (Elsevier, 2013-01)
      Cardiomyopathy is associated with cardiac Na(+) channel downregulation that may contribute to arrhythmias. Previously, we have shown that elevated intracellular NADH causes a decrease in cardiac Na(+) current (I(Na)) ...