Now showing items 1-5 of 5

    • African Ancestry Is Associated with Asthma Risk in African Americans 

      Flores, Carlos; Ma, Shwu-Fan; Pino-Yanes, Marı´a; Wade, Michael S.; Pe´rez-Me´ndez, Lina; Kittles, Rick A.; Wang, Deli; Papaiahgari, Srinivas; Ford, Jean G.; Kumar, Rajesh; Garcia, Joe G. N. (Public Library of Science, 2012-01)
      Background: Asthma is a common complex condition with clear racial and ethnic differences in both prevalence and severity. Asthma consultation rates, mortality, and severe symptoms are greatly increased in African descent ...
    • Iron deficiency modifies gene expression variation induced by augmented hypoxia sensing 

      Zhang, Xu; Zhang, Wei; Ma, Shwu-Fan; Miasniakova, Galina; Sergueeva, Adelina; Ammosova, Tatiana; Xu, Min; Nekhai, Sergei; Nourai, Mehdi; Wade, Michael S.; Prchal, Josef T.; Garcia, Joe G. N.; Machado, Roberto F.; Gordeuk, Victor R. (Elsevier Inc., 2014-01)
      In congenital Chuvash polycythemia (CP), VHLR200W homozygosity leads to elevated hypoxia inducible factor (HIF) levels at normoxia. CP is often treated by phlebotomy resulting in iron deficiency, permitting us to examine ...
    • MicroRNAs Implicated in Dysregulation of Gene Expression Following Human Lung Transplantation 

      Zhang, Wei; Zhou, Tong; Ma, Shwu-Fan; Machado, Robert F.; Bhorade, Sangeeta M.; Garcia, Joe G.N. (2013-08-08)
      Background: Lung transplantation remains the only viable treatment option for the majority of patients with advanced lung diseases. However, 5-year post-transplant survival rates remain low primarily secondary to chronic ...
    • MicroRNAs implicated in dysregulation of gene expression following human lung transplantation 

      Zhang, Wei; Zhou, Tong; Ma, Shwu-Fan; Machado, Robert F.; Bhorade, Sangeeta M.; Garcia, Joe GN. (SpringerOpen, 2013-08-08)
      Background: Lung transplantation remains the only viable treatment option for the majority of patients with advanced lung diseases. However, 5-year post-transplant survival rates remain low primarily secondary to ...
    • Peripheral Blood Gene Expression as a Novel Genomic Biomarker in Complicated Sarcoidosis 

      Zhou, Tong; Zhang, Wei; Sweiss, Nadera J.; Chen, Edward S.; Moller, David R.; Knox, Kenneth S.; Ma, Shwu-Fan; Wade, Michael S.; Noth, Imre; Machado, Roberto F.; Garcia, Joe G. N. (Public Library of Science, 2012-09)
      Sarcoidosis, a systemic granulomatous syndrome invariably affecting the lung, typically spontaneously remits but in ,20% of cases progresses with severe lung dysfunction or cardiac and neurologic involvement (complicated ...