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    • Combined Loss of Tet1 and Tet2 Promotes B Cell, but Not Myeloid Malignancies, in Mice. 

      Zhao, Z; Chen, L; Dawlaty, MM; Pan, F; Weeks, O; Zhou, Y; Cao, Z; Shi, H; Wang, J; Lin, L; Chen, S; Yuan, W; Qin, Z; Ni, H; Nimer, SD; Yang, FC; Jaenisch, R; Yin, P; Xu, M (Elsevier (Cell Press), 2015-11-24)
      TET1/2/3 are methylcytosine dioxygenases that regulate cytosine hydroxymethylation. Tet1/2 are abundantly expressed in HSC/HPCs and are implicated in hematological malignancies. Tet2 deletion in mice causes myeloid ...