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Direct Thrombin Inhibitors: Use and Consequences in Patients with Heparin-Induced Thrombocytopenia
Heparin-induced thrombocytopenia (HIT) is an immunologic response to heparin exposure that may lead to thrombosis. Argatroban and bivalirudin are two commonly used direct thrombin inhibitors (DTIs) for the prevention of ...
Navigating Safety of Anticoagulant Use From Precision Medicine to Direct Oral Anticoagulants
Background: This dissertation focuses on assessing avenues for safe delivery of oral anticoagulants. In that, three studies have been undertaken to address gaps in practice pertaining to Vitamin K Antagonist (VKA) and ...