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Effects of Fenofibrate on CYP2D6 and Regulation of ANG1 and RNASE4 by the FXR Agonist Obeticholic Acid
CYP2D6 is a major drug metabolizing enzyme that exhibits large interindividual variability, in part due to differential transcriptional regulation of CYP2D6; however, the factors controlling transcriptional regulation of ...
Transcriptional Regulation of Cytochrome P450 2D6 by Small Heterodimer Partner
Cytochrome P450 2D6 (CYP2D6) is a major drug-metabolizing enzyme, responsible for eliminating ~20% of marketed drugs. Of note, CYP2D6 activity exhibits large interindividual variability, but the factors leading to this ...