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Closing the In Vitro/In Vivo Gap in Tuberculosis Drug Discovery
This study establishes a new anti-M. tuberculosis (M. tb) drug lead screening scheme that integrates in vitro and in vivo methods for early detection of bioactive constituents during the purification of nature-derived ...
Antibiotics from Aquatic-Derived Actinomycete Bacteria that Inhibit M. tuberculosis
The World Health Organization (WHO) estimated that 1.5 million deaths were attributed to TB infection in 2014. Of these, 190,000 fatalities were a result of multidrug- and extensively drug-resistant strains of M. tuberculosis. ...