Now showing items 1-4 of 4
Analysis of Carotenoids Using LC-MS-MS with Ion Mobility Spectrometry and Photoionization
Carotenoids are naturally occurring fat-soluble pigments found principally in bacteria and plants including edible plants. Because of their extensively conjugated carbon-carbon double bond system, carotenoids are potent ...
A High Throughput LC-MS Platform for the Discovery of Autotaxin Inhibitors
The bioactive group of lipids, the eicosanoids, which includes lysophospholipids and their derivatives, are lipid mediators formed from arachidonic acid. Class 1 lipid mediators include sphingosine-1-phosphate (S1P), ...
ADMEt Evaluation of Anti-tuberculosis Compounds and New Methodologies Development
Tuberculosis (TB) is among the top three life-threatening infectious diseases in developing countries. Therefore, there is a great need to discover and develop novel anti-TB drugs. The current dissertation research focused ...
Serum Metabolome and Proteome Effects of Phytoestrogenic Dietary Supplements in Postmenopausal Women
A Phase II clinical trial assessing the efficacy of two dietary botanical supplements, black cohosh (Actaea racemosa) and red clover (Trifolium pretense) at reducing vasomotor symptoms in postmenopausal women was completed. ...