Now showing items 1-2 of 2
Selective Estrogen Mimics for the Treatment of Tamoxifen-Resistant, PKCalpha-Overexpressing Breast Cancer
Breast cancer is the most common female malignancy, affecting 1 in 8 women. Resistance to the antiestrogen tamoxifen (TAM), whether de novo or acquired, is a major clinical obstacle. Although recent clinical trials have ...
Interactions of Dendritic Nanomaterials with Skin Layers and Their Applications in Topical Drug Delivery
The barrier functions of the stratum corneum and the epidermal layers present a tremendous challenge in achieving effective transdermal delivery of drug molecules. Among many nanocarriers that have been tested to improve ...